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CHES Faculty Member
- Jinchuan Xing
- Associate Professor, Genetics
- Focus Area: Evolutionary and Modern Human Genetics
- Email: firstname.lastname@example.org
- ACADEMIC BIOGRAPHY:
Jinchuan Xing joined Department of Genetics as an Assistant Professor at Rutgers in 2012. Dr. Xing is a human/primate geneticist and received his Ph.D. from Louisiana State University in 2005. After spending an additional year at LSU as a postdoctoral fellow, Dr. Xing moved to University of Utah as a postdoctoral fellow and studied human population genetics and natural selection until 2011.
- CURRENT PROJECTS:
Dr. Xing's current projects include studying the evolutionary history of human populations, and investigating the phylogeny and hybridization in macaques.
Human demographic history and population diversity
Disease-causing genes identification using genome-wide data
Fan Z., A. Zhou, N. Osada, J. Yu, J. Jiang, P. Li, L. Du, L. Niu, J. Deng, H. Xu, J. Xing, B. Yue, and J. Li (2018) Ancient hybridization and admixture in macaques (genus Macaca) inferred from whole genome sequences. Molecular Phylogenetics and Evolution 127:376-386
Rustagi, N., A. Zhou, W. S. Watkins, E. Gedvilaite, S. Wang, N. Ramesh, D. Muzny, R. A. Gibbs, L. B. Jorde#, F. Yu#, and J. Xing# (2017) Extremely low-coverage whole genome sequencing in South Asians captures population genomics information. BMC Genomics 18:396
The Marmoset Genome Sequencing and Analysis Consortium (2014) The common marmoset genome provides insight into primate biology and evolution. Nature Genetics 46:850-857
Wang S., J. Lachance, S. Tishkoff, J. Hey, and J. Xing# (2013) Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from non-African populations. Genome Biology and Evolution 5:2075-2081
Xing J.*, T. Wuren*, T. S. Simonson*, W. S. Watkins, D. J. Witherspoon, W. Wu, G. Qin, C. D. Huff, L. B. Jorde, and R. L. Ge (2013) Genomic analysis of nature selection and phenotypic variation in high-altitude Mongolians. PLoS Genetics 9:e1003634
Xing J., W. S. Watkins, Y. Hu, C. D. Huff, A. Sabo, D. M. Muzny, M. J. Bamshad, R. A. Gibbs, L. B. Jorde, and F. Yu (2010) Inference of human expansion in Eurasia and genetic diversity in India. Genome Biology 11:R113
Xing J., W. S. Watkins, D. J. Witherspoon, Y. Zhang, S. L. Guthery, R. Thara, B. J. Mowry, K. Bulayeva, R. B. Weiss, and L. B. Jorde (2009) Fine-scaled human genetic structure revealed by SNP microarrays. Genome Research 19:815-825
Xing J., D. J. Witherspoon, D. A. Ray, M. A. Batzer, and L. B. Jorde (2007) Mobile elements and primate evolution. American journal of physical anthropology Suppl 45:2-19
Rhesus Macaque Genome Sequencing and Analysis Consortium (2007) Evolutionary and biomedical insights from the rhesus macaque genome. Science 316:222-234
- RESEARCH INTERESTS:
The long-term research interest of his laboratory is to understand the mechanisms and consequences of human genomic variation, with focuses on mobile DNA elements, evolutionary genetics, and human disease. They will combine computational and experimental tools to perform genome-wide analyses. His previous projects involve elucidating human population history and genetic adaptation at both global and regional scale, with or without disease implication.